Product Overview
Guanidine Thiocyanate is widely used in molecular biology, diagnostics and pharmaceuticals.
In molecular biology, it is a key component in RNA extraction buffers, protein extraction and nucleic acid purification. It works by inactivating RNases and DNases which can prevent nucleic acid degradation. RNA extraction is essential for the PCR and sequencing processes. The usage of Guanidine Thiocyanate in RNA extraction buffers is standard practice in molecular biology and is broadly recognized for its effectiveness in achieving high-quality RNA extracts. During the pandemic, Guanidine Thiocyanate is used in lysis buffer solution which isolates and extracts the viral RNA for a sample, making it a crucial component in Covid-19 test kits.
In pharmaceuticals, it is used to unfolds proteins for refolding studies and vaccine production.
|
CAS RN |
593-84-0 |
|
Molecular Formula |
CH5N3.CHNS |
| Molecular Weight | 118.16 g/mol |
|
Synonyms |
Guanidinium isothiocyanate, |
|
Appearance |
White crystalline powder |
Specification
|
Substance |
Value |
Unit |
|
Assay |
>= 99.5 |
% |
|
NH4Cl |
<= 0.1 |
% |
|
Water Content |
<= 0.3 |
% |
|
Ash |
<= 0.1 |
% |
|
Melting Point |
118 -121 |
℃ |
|
pH (11.8% Aqueous Solution) |
6 ± 1 |
|
|
UV Absorbance @ 260nm |
<= 0.2 |
|
|
UV Absorbance @ 280nm |
<= 0.05 |
|
|
Fe |
<= 0.1 |
ppm |
Packaging
- Inner: Polyethylene bags (25kg)
- Outer: Aluminium foil bag and fibre drum
Safety
- Irritable to eyes and skin upon contact
- Irritable to respiratory system if inhaled
- Harmful if swallowed
Storage Conditions
Keep in a cool and dry place.
Our Advantages
The product conforms to ISO 9001:2015.
We are the first factory in China to manufacture Guanidine Thiocyanate since 2003. Over the years, we have improved and perfected the production procedure and established the standards of product quality. We are capable of producing 300 tons of Guanidine Thiocyanate yearly.
