Product Overview
Guanidine Hydrochloride (Pharmaceutical Grade) is used in bio-pharmaceuticals, diagnostics and researches.
In bio-pharmaceuticals and researches, Guanidine Hydrochloride is used to unfold proteins for refolding studies (e.g., monoclonal antibodies study). It is also used in inclusion body solubilization. For RNA/DNA extraction, it works by disrupting hydrogen bonds in PCR, sequencing and mRNA vaccine production.
In diagnostics, Guanidine Hydrochloride works as extraction buffers for isolating nucleic acids from specimens and therefore is an essential part in test kits for viral RNA/DNA.
|
CAS RN |
50-01-1 |
|
Molecular Formula |
CH5N3.HCl |
|
Molecular Weight |
95.53 g/mol |
|
Synonyms |
Guanidinium chloride, |
|
Appearance |
White crystalline powder |


Specification
|
Substance |
Value |
Unit |
|
Assay |
>= 99.5 |
% |
|
NH4Cl |
<= 0.05 |
% |
|
Water Insoluble Substance |
<= 0.02 |
% |
|
Water Content |
<= 0.3 |
% |
|
Ash |
<= 0.02 |
% |
|
Solubility Test (In Water) |
Pass |
Pass / Fail |
|
Melting Point |
183 - 188 |
℃ |
|
pH (4% Aqueous Solution) |
6.4 ± 0.2 |
|
|
UV Absorbance @ 260nm |
<= 0.04 |
|
|
UV Absorbance @ 280nm |
<= 0.02 |
Packaging
- Inner: Polyethylene bags (25kg)
- Outer: Aluminium foil bag and fibre drum



Safety
- Irritable to eyes and skin upon contact
- Irritable to respiratory system if inhaled
- Requires Personal Protective Equipment (PPE): gloves, goggles and dust mask
Storage Conditions
Keep in a cool, dry and well-ventilated place.
Our Advantages
The product conforms to ISO 9001:2015.
We are the first plant in China to manufacture Guanidine Hydrochloride (Pharmaceutical Grade) and since then has over 22 years of experience. The pharmaceutical grade Guanidine Hydrochloride is our flagship product and has been sold to many countries overseas (e.g., German, United States, Japan). Its quality is well recognized.

