CAS RN: 30727-14-1
Assay (GC) >= 97%
Pyrrole
Your Leading Pyrrole Supplier
Hubei Yuecheng Dehong Biotechnology Co., Ltd. is a manufacturer of Guanidine Hydrochloride and Guanidine Thiocyanate and later expanded its production line to other chemical products. Yue Cheng De Hong is responsible for distributing the final products which are chemical intermediates in pharmaceutical, agrochemical, metallurgy and speciality chemical synthesis to its end consumers. After the reorganization, De Hong will be more committed to delivering better services to its customers as a distribution division. We offer a wide variety of pyrroles, including N-Ethyl-3-hydroxypyrrolidine, N-Methyl-3-hydroxypyrrolidine, and others.
Why Choose Us?
Rich Experience
Yue Cheng which has over 20 years of expertise since 2003 in the production and distribution of chemical products.
Professional Team
We are a group of professionals with years of experience in sales of chemical goods, and potential clients in a much more dedicated way.
Wide Product Range
We sell over 60 different chemical products, covering from agrochemical intermediate, pharmaceutical intermediate, and raw materials for cosmetics and hair products.
Quality Assurance
The company has established comprehensive product standards and specifications, and all chemical products meet the requirements of the ISO 9001 quality management system.
Types of Pyrrole
N-Ethyl-3-hydroxypyrrolidine
N-Ethyl-3-hydroxypyrrolidine has major applications in the fields pharmaceuticals, agrochemicals and chemical researches. It is an essential drug intermediate for making CNS drugs, specifically antidepressants and antipsychotics by acting as a modulator for dopamine and serotonin.
N-Methyl-3-hydroxypyrrolidine
N-Methyl-3-hydroxypyrrolidine is the drug intermediate that can be used in the synthesis of antipsychotics by acting as a modulator for dopamine receptor. It is also used in the synthesis of antivirals by acting as HCV protease inhibitor and local anesthetics through its pyrrolidine derivatives.
Specifications of Pyrrole
|
CAS RN |
13220-33-2 |
|
Molecular Formula |
C5H11NO |
|
Molecular Weight |
101.15 g/mol |
|
Synonyms |
1-Methyl-3-pyrrolidinol, |
|
Appearance |
Colorless to pale yellow liquid |
Properties of Pyrrole
The odour of pyrrole is a kind of nutty odour. It is a colourless volatile liquid but when exposed to air it changes its colour easily and darkens. Before any application, it is usually purified.
The IUPAC name of pyrrole is 1H-Pyrrole.
Similar to thiophene and futon compounds it is also a five-membered aromatic heterocyclic compound.
Unlike furan and thiophene, it features a dipole in which the end with a positive charge is on the side of the heteroatom with a dipole moment of 1.58 D.
Pyrrole is a weakly basic compound with a conjugate acid dissociation constant of (pKa) of −3.8.
The pyrrolinium cation (C4H6N+) which is most thermodynamically stable is formed through protonation at the 2nd position.
When pyrrole is substituted with substituents of alkyl it provides a more basic molecule, for example, tetramethyl pyrrole has a conjugate acid pKa of +3.7.
It is also a weakly acidic compound at the nitrogen and hydrogen position, with an acid dissociation constant value of 16.5.
The molecular weight of pyrrole is 67.09 g/mole.
The boiling point is 130.5°C (266.9°F) and the melting point is -23°C (-9.4°F).
Uses of Pyrrole
The derivatives of pyrrole and pyrrole themselves are widely used as an intermediate in the synthesis of agrochemicals, medicines, dyes, pharmaceuticals, perfumes, photographic chemicals and other organic compounds. For example, heme and chlorophyll are the derivatives of pyrrole that are made by four pyrrole ring formation of the porphyrin ring system.
Pyrrole derivatives are used in medicinal uses such as enzyme inhibiting, anti-microbial, anti-viral, antitubercular, anti-malarial, anti-inflammatory and anticancer properties. Compounds formed with rings of the pyrrole are also precursors to certain drugs.
Pyrroles are taken in the application as scarlet, lightfast red and carmine pigments.
Packaging of Pyrrole
• Plastic and Iron Drum (50kg)
Storage Conditions of Pyrrole
•Store in tightly closed containers in a cool, well-ventilated area away from sunlight, plastic, rubber and coatings.
•Sources of ignition, such as smoking and open flames, are prohibited where pyridine is used, handled, or stored.
•Metal containers involving the transfer of pyridine should be grounded and bonded.
•Use only non-sparking tools and equipment, especially when opening and closing containers of pyridine.
Transportation of Pyrrole
FAQ
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N-Ethyl-3-hydroxypyrrolidine, N-Methyl-3-hydroxypyrrolidine, pyrrole