Pharmaceutical Intermediate

Your Leading Pharmaceutical Intermediate Supplier

 

Hubei Yuecheng Dehong Biotechnology Co., Ltd. is a manufacturer of Guanidine Hydrochloride and Guanidine Thiocyanate and later expanded its production line to other chemical products. Pharma intermediates are chemical compounds used as building blocks in the synthesis of active pharmaceutical ingredients (APIs). They undergo further chemical reactions to form the desired APIs. We offer a wide variety of Pharmaceutical Intermediates with diverse applications, including Amidinothiourea, Aminoguanidine Bicarbonate, Methyl 4-bromophenylacetate, 3-Bromobenzaldehyde, p-Bromobenzaldehyde, and more.

 

 
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Why Choose Us?
 
 
 

Rich Experience

Yue Cheng which has over 20 years of expertise since 2003 in the production and distribution of chemical products.

 
 

Professional Team

We are a group of professionals with years of experience in sales of chemical goods, and potential clients in a much more dedicated way.

 
 

Wide Product Range

We sell over 60 different chemical products, covering from agrochemical intermediate, pharmaceutical intermediate, and raw materials for cosmetics and hair products.

 
 

Quality Assurance

The company has established comprehensive product standards and specifications, and all chemical products meet the requirements of the ISO 9001 quality management system.

 

 

Types of Pharmaceutical Intermediate
 

Dicyandiamide (Pharmaceutical Grade)
Dicyandiamide, also known as DCD, is an important chemical compound with various industrial applications. Its major application is to be used as a latent curing agent for epoxy resins in composites, adhesives and coatings.

 

Amidinothiourea
Amidinothiourea is the crucial intermediate to synthesize famotidine, which is a histamine-2 (H2) receptor antagonist that prevents acid reflux and inhibits the production of stomach acid.

 

Methyl 4-bromophenylacetate
Methyl 4-bromophenylacetate has a variety of applications as a reactive reagent. Moreover, it is a green reagent and can transform various functional groups into other upgraded and high-valued derivatives. It is crucial in achieving sustainability.

Dicyandiamide (Technical Grade / Industrial Grade)

 

4-Bromophenethyl Alcohol

P-Bromobenzaldehyde

P-Bromobenzaldehyde is a benzaldehyde derivative. In the field of medicine, p-Bromobenzaldehyde is found to have antidepressant effects and was tested for anxiolytic effects.

 

4-Bromotoluene

4-Bromotoluene / p-Bromotoluene is part of the halogenated aromatic compound class. It is widely used in organic synthesis, pharmaceuticals and agrochemicals.

 

Methyl 3-aminocrotonate

Methyl 3-aminocrotonate has a wide range of applications in pharmaceutical, agriculture and chemistry due to its versatile chemical properties and reactivity.

 

Specifications of Pharmaceutical Intermediate

 

 

Substance

Value

Unit

Impurity Precipitation Test

Acceptable

Acceptable/Not Acceptable

Purity

>= 99.5

%

Water

<= 0.30

%

Ash

<= 0.05

%

Melting Point

209 - 212

Calcium

<= 200

ppm

Solution Test

Acceptable

Acceptable/Not Acceptable

 

Characteristics of Pharmaceutical Intermediate

Therapeutic Effect

APIs are the active agents in drugs that treat specific conditions, delivering the main therapeutic benefit.

High Purity and Quality Standards

APIs must meet stringent regulations to ensure their quality, purity, and effectiveness.

3-Bromophenylacetic Acid
Amidinothiourea

Precise Manufacturing Process

Produced through complex chemical or biological processes, APIs require meticulous control to achieve consistency across batches.

Combination with Excipients

In a finished drug, APIs are mixed with excipients, which aid in the drug's absorption, stability, and overall delivery to the body.

 

Precautions for Using Pharmaceutical Intermediate

Handling pharma intermediates requires careful attention to safety. Here's how you can ensure safe handling and use:

 
 

Personal Protective Equipment (PPE)

Workers should wear appropriate PPE, including gloves, goggles, and respirators, when handling pharma intermediates to prevent skin contact and inhalation of dust.

 
 
 

Safe Storage

Store pharma intermediates in a cool, dry, and well-ventilated area, away from incompatible materials such as strong acids and oxidizing agents.

 
 
 

Spill and Disposal Procedures

Implement spill response and disposal procedures to safely manage accidental releases of pharma intermediates. Dispose of waste products according to local environmental regulations.

 

 

Applications of Pharmaceutical Intermediate

 
Drug Development

Pharma intermediates play a central role in drug development:
Synthesis of Active Pharmaceutical Ingredients (APIs): Use pharma intermediates as key starting materials in the synthesis of APIs. These intermediates undergo specific chemical reactions to transform into APIs, the biologically active components in drugs.


Custom Synthesis: Pharmaceutical companies often require custom synthesis of pharma intermediates to meet the specific needs of new drug development. You can design and produce custom intermediates according to the requirements of the target API, ensuring the successful development of new drugs.


Scale-Up Production: Once a pharma intermediate has been identified as effective in the synthesis of an API, scale up its production. This scale-up production is crucial for manufacturing sufficient quantities of the API for clinical trials and eventual commercial production.

Pharmaceutical Manufacturing

In pharmaceutical manufacturing, pharma intermediates serve as the foundation for producing various drugs:
Bulk Drug Manufacturing: Use pharma intermediates in the large-scale production of bulk drugs. You can synthesize these intermediates and then convert them into APIs, which are further processed into dosage forms like tablets, capsules, and injectables.


Contract Manufacturing: Many pharmaceutical companies outsource the production of pharma intermediates to contract manufacturers. These contract manufacturers specialize in producing high-quality intermediates that meet stringent industry standards.


Formulation Development: Use pharma intermediates in formulation development to create the final drug products. Combine the intermediates with excipients and other ingredients to create stable, effective, and safe pharmaceutical formulations.

 

Packaging of Pharmaceutical Intermediate

 

 

Inner:

Polyethylene bags (25kg)

Outer:

Woven bags or fibre drum

 

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Storage of Pharmaceutical Intermediate

 

 

》Keep in a cool, dry and well-ventilated place.
》It should be kept away from heat, flame and any source of ignition.

 

Transportation of Pharmaceutical Intermediate

 

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FAQ

 

Q: Which kind of payment terms do you accept?

A: You can pay by TT, Western Union , Alibaba trade assurance etc .

Q: Can you give me a discount price?

A: Surely, It depends on your qty.

Q: How can I get a sample?

A: Free samples for some products is available, but freight charges will be at your account and the charges will be return to you or deduct from your formal order in the future.

Q: How to confirm the Product?

A: You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send US your product specifications and requests,we will manufacture the products according to your requests.

Q: How do you treat quality complaint?

A: First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for eplacement or refund your loss.

We're well-known as one of the leading pharmaceutical intermediate manufacturers and suppliers in China. Please rest assured to buy bulk high quality pharmaceutical intermediate for sale here from our factory. For quotation, contact us now.

2-Bromophenylacetonitrile, 3-Bromotoluene, Methyl 4 Bromobenzoate